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Table 3 Mean serum IGF-1, mean height, and mean weight with respect to various CS in different types of maturers

From: Serum IGF-1 levels as a clinical tool for optimizing orthodontic treatment timing

Cervical stage Mean age (years) 95% confidence interval (years) Advance maturer Average maturer Delayed maturer
   Lower bound Upper bound Mean IGF-1 (ng/ml) Mean height (in.) Mean weight (kg) Mean IGF-1 (ng/ml) Mean height (in.) Mean weight (kg) Mean IGF-1 (ng/ml) Mean height (in.) Mean weight (kg)
CS-3 13.4 13.2 13.7 317 61.9 40.2 288 61.3 39.8 339 61.6 42.1
     (226–372) (59–64) (36–43) (171–369) (58–62) (38–42) (253–389) (59–65) (39–46)
     (<13.2 years) (13.2–13.7 years) (>13.7 years)
CS-4 15.9 15.6 16.2 381 65.2 42.4 318 65.2 42.8 352 66.3 48.2
     (300–525) (62–68) (38–46) (252–398) (58–71) (37–52) (275–427) (64–68) (42–50)
     (<15.6 years) (15.6–16.2 years) (>16.2 years)
CS-5 17.3 17.0 17.5 293 67.6 51.1 278 68.0 57.1 267 67.5 52.6
     (222–372) (66–68) (45–56.5) (206–311) (65–70) (52–64) (241–304) (67–68) (48–60)
     (<17.0 years) (17.0–17.5 years) (>17.5 years)
  1. Advance maturers, subjects with age less than the lower bound age limit in each cervical stage. Average maturers, subjects with age within the upper and lower bound age limit in each cervical stage. Delayed maturers, subjects with age above the upper bound age limit in each cervical stage.