Comparison of the effects of ibuprofen and acetaminophen on PGE2 levels in the GCF during orthodontic tooth movement: a human study

Progress in Orthodontics

Table 1 Intragroup and intergroup comparisons of PGE ₂ levels (ng/mL)

	T ₀	T ₁	T ₂	T ₃	PGE₂levels ( p)
	T ₀	T ₁	T ₂	T ₃	T₀vs. T₁	T₁vs. T₂	T₂vs. T₃	T₀vs. T₂	T₀vs. T₃	T₁vs. T₃
Intragroup
Group I	31.90 ± 8.88	47.94 ± 10.28	36.99 ± 8.80	32.35 ± 8.96	0.001	0.001	0.001	0.001	0.463	0.001
Group A	32.85 ± 9.09	63.00 ± 9.08	47.70 ± 9.24	33.01 ± 10.42	0.001	0.001	0.001	0.001	0.875	0.001
Group C	34.15 ± 13.59	67.15 ± 16.79	51.60 ± 16.65	35.04 ± 13.83	0.001	0.001	0.001	0.001	0.753	0.001
Intergroup (p)
I vs.A	0.963	0.0006	0.011	0.490
I vs.C	0.963	0.002	0.011	0.679
A vs.C	0.747	0.421	0.520	0.963

T₀ = baseline, T₁ = 24 h, T₂ = 48 h, T₃ = 168 h. I, ibuprofen group; A, acetaminophen group; C, control group.