Item | Description |
---|---|
Title | |
1. Title | Identification of the study as a systematic review, meta-analysis, or both |
Background | |
2. Objectives | The research question including components such as participants, interventions, comparators, and outcomes |
Methods | |
3. Eligibility criteria | Study and report characteristics used as criteria for inclusion |
4. Information sources | Key databases searched and search dates |
5. Risk of bias | Methods of assessing risk of bias |
Results | |
6. Included studies | Number and type of included studies and participants and relevant characteristics of studies |
7. Synthesis of results | Results for main outcomes (benefits and harms), preferably indicating the number of studies and participants for each. If meta-analysis was done, include summary measures and confidence intervals. |
8. Description of the effect | Direction of the effect (i.e., which group is favored) and size of the effect in terms meaningful to clinicians and patients |
Discussion | |
9. Strengths and limitations of evidence | Brief summary of strengths and limitations of evidence (e.g., inconsistency, imprecision, indirectness, or risk of bias, other supporting or conflicting evidence) |
10. Interpretation | General interpretation of the results and important implications |
Other | |
11. Funding | Primary source of funding for the review |
12. Registration | Registration number and registry name |