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Table 1 Mean percent pain scores on visual analogue scale (VAS) with estimates ANOVA with repeated measures (RM)

From: The effect of a lidocaine/prilocaine topical anesthetic on pain and discomfort associated with orthodontic elastomeric separator placement

Duration (minutes) Number Mean ± SD (TA) Mean ± SD (Placebo) Estimated grand mean (95% CI) p value (ANOVA RM)
2 50 11.53 ± 11.27 20.91±20.74 16.22 (12.91–19.53)  
4 50 4.52 ± 7.40 14.99±13.23 9.76 (7.63–11.88) F = 40.7
6 50 2.65 ± 6.10 11.79±11.13 7.22 (5.44–9.00) (p = 0.001)
8 50 0.80 ± 2.79 8.90 ± 9.37 4.85 (3.48–6.22)  
10 50 0.30 ± 0.95 7.27±10.12 3.78 (2.36–5.12)