Study characteristics | Li et al. 2010 [17] | Braga et al. 2011 [16] | Villarino et al. 2011 [20] | Zhang et al. 2011 [21] | Plut et al. 2015 [22] | Arita et al. 2016 [15] |
---|---|---|---|---|---|---|
Title | 1 | 1 | 1 | 1 | 1 | 1 |
Abstract | 1 | 1 | 1 | 1 | 1 | 1 |
Introduction | ||||||
Adequate background | 1 | 1 | 1 | 1 | 1 | 1 |
Objectives described adequately | 1 | 1 | 1 | 1 | 1 | 1 |
Method | ||||||
Ethical statement | 1 | 1 | 1 | 0 | 0 | 1 |
Blinding | 1 | 0 | 0 | 0 | 0 | 0 |
Description of animal groups | 1 | 1 | 1 | 1 | 1 | 1 |
Adequate experimental procedures | 1 | 1 | 1 | 1 | 1 | 1 |
Experimental animals | 1 | 1 | 1 | 1 | 1 | 1 |
Housing | 1 | 0 | 0 | 0 | 0 | 1 |
Appropriate sample size | 0 | 1 | 0 | 0 | 0 | 0 |
Randomization of animals | 0 | 0 | 0 | 0 | 0 | 0 |
Experimental outcomes | 1 | 1 | 1 | 1 | 1 | 1 |
Statistics | 1 | 1 | 1 | 1 | 1 | 1 |
Results | 1 | |||||
Baseline data | 1 | 1 | 1 | 1 | 1 | 1 |
Number analyzed | 1 | 1 | 1 | 1 | 1 | 1 |
Adequate outcomes | 1 | 1 | 1 | 1 | 1 | 1 |
Reporting of adverse effects | 0 | 0 | 0 | 0 | 0 | 0 |
Discussion | ||||||
Adequate interpretation of results | 1 | 1 | 1 | 1 | 1 | 1 |
Clinical implications | 1 | 1 | 1 | 1 | 1 | 1 |
Funding information | 1 | 1 | 0 | 0 | 0 | 1 |
Total score (out of 20) | 17 | 16 | 14 | 13 | 13 | 16 |