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Table 7 Explorative regression analyses with simplified plaque index or S. sanguinis counts as dependent variable and stratified by appliance subgroup

From: Salivary levels of cariogenic bacterial species during orthodontic treatment with thermoplastic aligners or fixed appliances: a prospective cohort study

    Aligners Brackets  
Outcome Factor Group b (95% CI) P SG b (95% CI) P SG P interaction
s-PlI Age Per year − 0.06 (− 0.23 to 0.11) 0.47 − 0.18 (− 0.43 to 0.07) 0.16 0.08
Gender Female Referent   Referent   
Male 0.25 (−0.61 to 1.10) 0.57 0.95 (0.23 to 1.67) 0.01  
Time T0 Referent   Referent   
T1 − 1.37 (− 2.04 to − 0.69) < 0.001 0.18 (− 0.48 to 0.84) 0.60  
T2 − 0.54 (− 1.29 to 0.21) 0.16 0.61 (− 0.49 to 1.71) 0.28  
s-PlI at T0 Per unit 0.53 (0.16 to 0.89) 0.005 0.20 (− 0.13 to 0.54) 0.24  
S. sanguinis Age Per year NT   NT   0.11
Gender Female NT   NT   
Male NT   NT   
Time T0 Referent   Referent   
T1 − 2.61 (− 4.89 to − 0.33) 0.03 9.03 (3.71 to 14.35) 0.001  
T2 − 1.50 (− 4.47 to 1.46) 0.32 2.70 (− 1.58 to 6.97) 0.22  
s-PlI at T0 per unit NT   NT   
  1. b unstandardized regression coefficient, CI confidence interval, NT not tested, Pinteraction P value for time differences between appliance subgroups (interaction time with appliance), PSG P for effects within each subgroup, s-PlI simplified plaque index