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Fig. 3 | Progress in Orthodontics

Fig. 3

From: Functional dysbiosis within dental plaque microbiota in cleft lip and palate patients

Fig. 3

Bacterial composition estimated from mRNA reads and comparative analysis of 16S rRNA-based and mRNA-based profiles. a In the bar charts, bacterial composition assigned using the NCBI nr at the genus level is presented as the relative abundance. Each color corresponds to a genus on the right side. b For the bacterial composition assigned with the HOMD for rc-rRNA and NCBI nr for mRNA reads, first coordinates in the PCoA are plotted with second coordinates in scatter graphs. For CLP subjects (on the left side), the rc-rRNA-based and mRNA-based compositions are indicated by red and yellow, respectively. For the control participants (on the right side), the rc-rRNA-based and mRNA-based compositions are indicated by blue and green, respectively. c The bar charts show the mean log2 ratio of the active taxa, defined as taxa with a log2 mRNA-to-rRNA ratio of ≥ 6. Group-specific active taxa are indicated by bold characters and filled circles (on the left side of names)

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