Table 3 GRADE evidence profile table about influence of heritability in main occlusal traits
From: Influence of heritability on occlusal traits: a systematic review of studies in twins
Certainty Assessment | ||||||||
|---|---|---|---|---|---|---|---|---|
No. of Studies | Study design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other consideration | Impact | Overall certainty of evidence |
Arch width | ||||||||
6 | OSa | Seriousb | Not serious | Not serious | Not serious | None | Arch width has an important heritability component | ⨁⨁◯◯ Low |
Arch length | ||||||||
5 | OSa | Seriousb | Not serious | Not serious | Not serious | None | Genetic determination can be demonstrated with a higher heritability coefficient for the maxillary arch than for the mandibular | ⨁⨁◯◯ Low |
Overjet | ||||||||
6 | OSa | Seriousb | Not serious | Not serious | Not serious | None | The heritability estimate for was not often mentioned, highlighting a strong environmental contribution to observed variation | ⨁⨁◯◯ Low |
Overbite | ||||||||
6 | OSa | Seriousb | Not serious | Not serious | Not serious | None | Heritability was weak for overbite, suggesting the presence of hidden environmental determinacies | ⨁⨁◯◯ Low |
Malalignment/intertooth space | ||||||||
5 | OSa | Seriousb | Not serious | Not serious | Not serious | None | The alignment of teeth, mainly in the mandibular arch, is under strong dominance of genetic factors | ⨁⨁◯◯ Low |
Sagittal molar relationship | ||||||||
4 | OSa | Seriousb | Not serious | Not serious | Not serious | None | It appears that the environmental component as the major determinant | ⨁⨁◯◯ Low |
Posterior crossbite | ||||||||
4 | OSa | Seriousb | Not serious | Not serious | Not serious | None | Although one study reports a high heritability value, most studies did not shown a genetic influence on this trait | ⨁⨁◯◯ Low |