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Table 2 Strategies for database searches (up to June 16th, 2020)

From: The effect of the local administration of biological substances on the rate of orthodontic tooth movement: a systematic review of human studies

Database

Search strategy

Hits

PubMed/Medline

((“Tooth Movement Techniques”[Mesh] OR “tooth movement”[tw] OR orthodont*[tw]) AND (“Cholecalciferol”[Mesh] OR “Growth Hormone”[Mesh] OR “growth hormone”[tw] OR “Parathyroid Hormone”[Mesh] OR “parathyroid hormone”[tw] OR PTH[tw] OR “Platelet-Rich Plasma”[Mesh] OR “platelet-rich plasma”[tw] OR PRP[tw] OR “platelet-rich fibrin”[tw] OR “Prostaglandins”[Mesh] OR prostaglandin[tw] OR prostaglandin*[tw] OR “Relaxin”[Mesh] OR relaxin[tw] OR “Thyroid Hormones”[Mesh] OR “Vitamins”[Mesh] OR “vitamin D”[tw] OR vitamin[tw] OR vitamin*[tw] OR calcitonin[tw] OR calcitriol[tw] OR tyrosine[tw])) NOT (“Animals”[Mesh] NOT (“Animals”[Mesh] AND “Humans”[Mesh]))

307

Scopus (Elsevier)

TITLE-ABS-Key((“tooth movement” OR orthodont*) AND (cholecalciferol OR “growth hormone” OR “parathyroid hormone” OR PTH OR “platelet-rich plasma” OR PRP OR “platelet-rich fibrin” OR prostaglandin OR prostaglandin* OR relaxin OR “thyroid hormone” OR “vitamin D” OR vitamin OR vitamin* OR calcitonin OR calcitriol OR *tyrosine))

594

Cochrane Central Register of Controlled Trials (CENTRAL) (Wiley)

All Text: (“tooth movement” OR orthodont*) AND (cholecalciferol OR “growth hormone” OR “parathyroid hormone” OR PTH OR “platelet-rich plasma” OR PRP OR “platelet-rich fibrin” OR prostaglandin OR prostaglandin* OR relaxin OR “thyroid hormone” OR “vitamin D” OR vitamin OR vitamin* OR calcitonin OR calcitriol OR *tyrosine)

69

CINAHL (Ebsco)

(MH Orthodontics+ OR TX “tooth movement” OR TX orthodont*) AND (MH Cholecalciferol OR TX cholecalcifereol OR MH Human Growth Hormone OR TX “growth hormone” OR MH Parathyroid Hormones+ OR TX “parathyroid hormone” OR TX PTH OR MH Platelet-Rich Plasma+ OR TX “platelet-rich plasma” OR TX PRP OR TX “platelet-rich fibrin” OR MH Prostaglandins+ OR TX prostaglandin OR TX prostaglandin* OR TX relaxin OR MH Thyroid Hormones+ OR TX “thyroid hormone” OR MH Vitamins+ OR TX “vitamin D” OR TX vitamin OR TX vitamin* OR MH Calcitonin OR TX calcitonin OR MH Calcitriol OR TX calcitriol OR MH Tyrosine OR TX *tyrosine)

Limit to: Human

140

Global Index Medicus (World Health Organization)

(“tooth movement” OR orthodont*) AND (cholecalciferol OR “growth hormone” OR “parathyroid hormone” OR PTH OR “platelet-rich plasma” OR PRP OR “platelet-rich fibrin” OR prostaglandin OR prostaglandin* OR relaxin OR “thyroid hormone” OR “vitamin D” OR vitamin OR vitamin* OR calcitonin OR calcitriol OR *tyrosine)

103

Dissertation Abstracts (ProQuest)

ab((“tooth movement” OR orthodont*) AND (cholecalciferol OR “growth hormone” OR “parathyroid hormone” OR PTH OR “platelet-rich plasma” OR PRP OR “platelet-rich fibrin” OR prostaglandin OR prostaglandin* OR relaxin OR “thyroid hormone” OR “vitamin D” OR vitamin OR vitamin* OR calcitonin OR calcitriol OR tyrosine)) OR ti((“tooth movement” OR orthodont*) AND (cholecalciferol OR “growth hormone” OR “parathyroid hormone” OR PTH OR “platelet-rich plasma” OR PRP OR “platelet-rich fibrin” OR prostaglandin OR prostaglandin* OR relaxin OR “thyroid hormone” OR “vitamin D” OR vitamin OR vitamin* OR calcitonin OR calcitriol OR tyrosine)) OR su((“tooth movement” OR orthodont*) AND (cholecalciferol OR “growth hormone” OR “parathyroid hormone” OR PTH OR “platelet-rich plasma” OR PRP OR “platelet-rich fibrin” OR prostaglandin OR prostaglandin* OR relaxin OR “thyroid hormone” OR “vitamin D” OR vitamin OR vitamin* OR calcitonin OR calcitriol OR tyrosine)) OR diskw((“tooth movement” OR orthodont*) AND (cholecalciferol OR “growth hormone” OR “parathyroid hormone” OR PTH OR “platelet-rich plasma” OR PRP OR “platelet-rich fibrin” OR prostaglandin OR prostaglandin* OR relaxin OR “thyroid hormone” OR “vitamin D” OR vitamin OR vitamin* OR calcitonin OR calcitriol OR tyrosine))

17

ClinicalTrials.gov

Condition/disease: Orthodontic OR “Tooth Movement”

Other Terms: cholecalciferol OR “growth hormone” OR “parathyroid hormone” OR PTH OR “platelet-rich plasma” OR PRP OR “platelet-rich fibrin” OR prostaglandin OR relaxin OR “thyroid hormone” OR vitamin OR calcitonin OR calcitriol OR tyrosine

4

ISRCTN Registry

(“tooth movement” OR orthodont*) AND (cholecalciferol OR “growth hormone” OR “parathyroid hormone” OR PTH OR “platelet-rich plasma” OR PRP OR “platelet-rich fibrin” OR prostaglandin OR prostaglandin* OR relaxin OR “thyroid hormone” OR “vitamin D” OR vitamin OR vitamin* OR calcitonin OR calcitriol OR *tyrosine)

0