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Table 5 Summary of risk of bias assessment for randomized studies—The Cochrane’s Collaboration’s tool

From: The effect of the local administration of biological substances on the rate of orthodontic tooth movement: a systematic review of human studies

Domain

Al-Hasani et al. [26]

McGorray et al. [28]

Tehranchi et al. [31]

Yussif et al. [42]

Varughese et al. [43]

El-Timamy et al. [32]

Randomization process

High

Some concerns

Some concerns

Some concerns

Low

Low

Deviations from intended interventions

Some concerns

Low

Low

Some concerns

Low

Low

Missing outcome data

Low

Low

Some concerns

Low

Low

Low

Measurement of the outcome

Some concerns

Low

Low

Unclear

Some concerns

Some concerns

Selection of the reported result

Low

Low

Low

Low

Some concerns

Low

overall

Some concerns

Low

Some concerns

Some concerns

Low

Low