Table 2 Summary of the data from included studies
From: Allergies/asthma and root resorption: a systematic review
1. Authorship | 2. Material | 3. Exposure | 4. Methodology | 5. Results | 6. Conclusions | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Author, year Study design | Risk factor/outcome M/F (n) Mean age ± SD (years) | Malocclusion (Mocl) Orthodontic device Mean treatment time of orthodontic treatment ± SD (years) | Asthma or allergies | Evaluated teeth Evaluation method | Incidence of root resorption (%)/prevalence of risk factors (%) | Odds ratio (OR) (IC 95%) p value | ||||
Control | Exposed | Control | Exposed | Control | Exposed | |||||
McNab et al. [14], 1999 Retrospective cohort | Patients without asthma 38M/59F 13.9 ± 1.8 years | Patients with asthma 18M/26F 14.5 ± 3.2 years | Mocl: N.I Fixed appliance, with or without headgear 1.9 ± 0.5 years | Mocl: NI Fixed appliance, with or without headgear 1.8 ± 0.4 years | Asthma | PM’s, mesio-buccal and disto-buccal roots of the upper 1st M, mesial and distal roots of the lower 1st M Panoramic radiography Sharpe scale | T0: Severe OIIRR: 0.93% T1: Severe OIIRR: 15.27% N. I | T0: Severe OIIRR: 2.3% T.1: Severe OIIRR: 13.15% N. I | OR=N.A Multivariate analysis: p=0.019 | - Although there is an association between root resorption and the asthma risk factor (p = 0.019), asthmatic and non-asthmatic individuals exhibited similar values of severe OIIRR. |
Melo et al. [15], 2018 Case-control | Patients with initial OIIRR 300M/314F 14.37 ± 2.76 years | Patients with severe OIIRR 32M/37F 15.09 ± 3.44 years | Mocl: Cl I=266 Cl II=319 Cl III=29 Fixed appliance 2.07 ± 0.93 years | Mocl: Cl I=24 Cl II=43 Cl III=2 Fixed appliance 2.72 ± 1.07 years | Asthma | Upper and lower incisors Periapical radiography Levander and Malmgren method | N.I With asthma=35% Without asthma= 65% | N.I With asthma=36.2% Without asthma=63.7% | OR= 1.05 (0.62-1.77) p=0.94 | -The prevalence of individuals with asthma was like the two groups. -There was no association between the risk factor asthma and OIIRR (p = 0.841) -Asthmatic and non-asthmatic individuals have the same chance of developing OIIRR (OR=1.05, 95% CI=0.62-1.77). |
Nishioka et al. [11], 2006 Case-control | Patients without OIIRR 18M/42F M: 15.9 ± 4.5 years F: 18.5 ± 5.2 years 17.7 ± 5.1 years | Patients with OIIRR 18M/42F M: 17.7 ± 5.7 years F: 16.4 ± 6.0 years 16.8 ± 5.9 years | Mocl: Cl I=10 Cl II=29 Cl III=21 Fixed appliance 2.96 ± 0.56 years | Mocl: Cl I=10 Cl II=29 Cl III=21 Fixed appliance 3.10 ± 1.19 years | Allergies and asthma | All teeth Panoramic radiography, measured with a digital pachymeter | N.I With allergies: 21% With asthma: 5% | N.I With allergies: 40% With asthma: 15% | Allergy risk factor: OR= 2.41 (1.08-5.37) p=0.04 Asthma risk factor: OR=3.35 (0.86-13.06) p=0.12 | -The prevalence of risk factors was higher in individuals with OIIRR. - Allergic individuals are more likely to develop OIIRR than non-allergic individuals (OR = 2.41, 95% CI = 1.08-5.37). -However, asthmatic, and non-asthmatic individuals have the same chance of developing OIIRR (OR=3.35, 95% CI=0.86-13.06). |
Owman-Moll et al. [17], 2000 Case-control | Patients with initial OIIRR 25 (N.I.) 13.4 a ±N. I | Patients with severe OIIRR 25 (N.I.) 13.4 a ±N. I | Mocl: N. I. Fixed appliance and lower lingual arch N. I | Mocl: N. I. Fixed appliance and lower lingual arch N. I | Allergy | Upper PM’s Histological analysis | N.I With allergies: 13.3% | N.I With allergies: 26.6% | OR=1.17 (0.38-3.75) p=1 | - The prevalence of allergies was higher in individuals with severe OIIRR. -However, allergic, and non-allergic individuals have the same chance of developing OIIRR (OR=1.17, 95% CI=0.38-3.75). |
Pastro et al. [19], 2018 Case-control | Patients with initial OIIRR 252M/255F 14.21 ± 2.45 years | Patients with severe OIIRR 40M/53F 14.57 ± 2.67 years | Mocl: Cl I=220 Cl II=269 Cl III=18 Fixed appliance 1.81 ± 0.83 years | Mocl: Cl I=38 Cl II=52 Cl III=3 Fixed appliance 2.41 ± 0.99 years | Allergy | Upper and lower incisors Periapical radiography Levander and Malmgren method | N.I With allergies: 42% Without allergy:58% | N.I With allergies: 49.46% Without allergy: 50.53% | OR=1.35 (0.86-2.1) p=0.22 | -The prevalence of allergies was higher in individuals with severe OIIRR. -There was no association between the allergy risk factor and OIIRR (p = 0.182). -Allergic and non-allergic individuals have the same chance of developing OIIRR (OR=1.35, 95% CI=0.86-2.1). |
Shim et al. [16], 2003 Case-control | Patients without OIIRR 25M/26F 15.40 ± 4.10 years | Patients with OIIRR 25M/26F 16.10 ± 3.30 years | Mocl: Cl I=15 Cl II=13 Cl III=23 Fixed appliance 2.31 ± 0.77 years | Mocl: Cl I=15 Cl II=14 Cl III=22 Fixed appliance 2.13 ± 0.73 years | Allergy and asthma | All teeth Panoramic radiography Measurement of root length on panoramic radiography | N.I With allergies: 31% With asthma: 5.88% | N.I With allergies: 49% With asthma: 17.64% | Allergy risk factor: OR= 2.10 (0.93-4.71) p=0.1 Asthma risk factor: OR=3.42 (0.87-13.5) p=0.12 | -The prevalence of allergies was higher in individuals with OIIRR, but without statistical significance (OR=2.1, 95%CI= 0.93-4.71). -The prevalence of asthma was statistically higher in individuals with OIIRR (p = 0.01). -However, asthmatic individuals have the same chance of developing OIIRR as non-asthmatic individuals (OR = 3.42, 95%CI = 0.87-13.5). |