Table 6 Summary of findings according to GRADE
RME compared with untreated control group for treatment of functional posterior cross bite | |
|---|---|
Patient or population: patients in mixed dentition had functional posterior crossbite Intervention: RME Comparison: untreated control group |
Outcomes | Anticipated absolute effects* (95% CI) | Relative effect (95% CI) | № of participants (studies) | Certainty of the evidence (GRADE) | Comments | |
|---|---|---|---|---|---|---|
Risk with untreated control group | Risk with RME | |||||
Maxillary intermolar width | MD 4.3 higher (2.05 higher to 6.55 higher) | – | 66 (1 RCT) | ⨁◯◯◯ VERY LOWa,b | RME may increase the maxillary intermolar width compared with control group but the evidence is very uncertain | |
Maxillary intercanine width | MD 2.6 higher (0.93 higher to 4.27 higher) | – | 66 (1 RCT) | ⨁◯◯◯ VERY LOWa,b | RME may increase the maxillary intercanine width compared with control group but the evidence is very uncertain | |
Mandibular intermolar width | MD 0 (1.51 lower to 1.51 higher) | – | 66 (1 RCT) | ⨁◯◯◯ VERY LOWa,b,c | The evidence is very uncertain about the effect of RME on mandibular intermolar width | |
Mandibular intercanine width | MD 0.8 higher (0.38 lower to 1.98 higher) | – | 66 (1 RCT) | ⨁◯◯◯ VERY LOWa,b,d | The evidence is very uncertain about the effect of RME on mandibular intercanine width | |
Mandibular midline correction | MD 1.8 lower (2.56 lower to 1.04 lower) | – | 66 (1 RCT) | ⨁◯◯◯ VERY LOWa,b | RME may reduce the mandibular midline deviation compared with control group but the evidence is very uncertain | |
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI) CI: Confidence interval; MD: Mean difference | ||||||
GRADE Working Group grades of evidence High certainty: We are very confident that the true effect lies close to that of the estimate of the effect Moderate certainty: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different Low certainty: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect Very low certainty: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect | ||||||