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Progress in Orthodontics
Fig. 3 | Progress in Orthodontics

Fig. 3

From: Role of mechano-sensitive non-coding RNAs in bone remodeling of orthodontic tooth movement: recent advances

Fig. 3

The mechanical transduction of mechanical stimulation and its effect on the expression of ncRNA. Different types of mechanical stimuli modulate cell membrane tension and further motivate calcium channels and other cation channel opening via the ECM and primary cilia. Additionally, integrins could directly sense mechanical signals through the ECM, which alter the expression of ncRNA by the activation of downstream signal pathways and mechanical transmission of the cytoskeleton

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