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Table 1 Summary of the data from included studies

From: Spontaneous changes in mandibular incisor crowding from mixed to permanent dentition: a systematic review

Author, year. Study design

Country

n (M/F)

Mean age (SD)

follow-up

Mandibular incisor crowding diagnosis

Secondary evaluations

Statistical analysis

Results

Conclusions

Mandibular incisor crowding in the mixed dentition (M/SD)

Mandibular incisor crowding in the permanent dentition (M/SD)

Mandibular incisor crowding change in the transition of dentition

(M/SD)

Sinclair and Little [19]

Retrospective cohort study

USA

65 (33/32)

9.06 years

4 years

Little index

Intra- and inter-arch measurements

Pearson's correlation and t-test

2.22 (1.23) mm

2.00 (1.17) mm

-0.17 (1.75) mm

Although the average amount of mandibular incisor crowding reduction is only 0.17 mm, the data variability is large

Sampson and Richards [18]

Prospective cohort study

Australia

47 (26/21)

8.91 (1.05) years

4 years

Leighton's method

PM/M position

t test, Pearson's correlation and multiple regression

G1

G2

G1

G2

G1

G2

Children with lower initial crowding (0.4 mm) may present a worsening of 0.6 mm ± 0.2 mm

0.4 ± 0.4 mm

1 ± 0.45 mm

1 ± 0.45 mm

0.7 ± 0.35 mm

0.6 ± 0.2 mm

-0.3 ± 0.2 mm

Hagberg [15]

Prospective cohort study

Sweden

24(14/10)

7 years (N.R)

6 years

Difference between incisor width and available space between deciduous canines

Canine eruption

Wilcoxon, Pearson and Spearman correlations

Male

Female

Male

Female

Male

Female

Mandibular incisor crowding tends to decrease in both sexes in the transition from mixed to permanent dentition after the eruption of permanent canines

1.49 mm (N.R)

1.49 mm (N.R)

0.40 mm (N.R)

0.65 mm

(N.R)

 − 1.09 mm (N.R)

 − 0.84 mm (N.R)

Arslan et al. [17]

Retrospective cohort study

Turkey

65 (29/36)

9.54 (1.42)

5 years

Little index

Intra/inter arch mx and md

t test

1.31 (0.78)

1.11 (0.86)

 − 0.19 (0.69)

Mandibular incisor crowding shows little self-correction in the dentition transition, related to leeway space and facial growth

Barros, et al. [16]

Retrospective cohort study

Brazil

42 (22/20)

8.66 (0.83)

4.58 (1.10) Years

Difference between incisor width and space between deciduous canines

Cephalometric and intra-arch md measurements

Wilcoxon, t test and multiple regression

G1 (≤ 2 mm)

0.73 (0.58)

G2 (≥ 2 mm)

3.96 (1.86)

G1 (≤ 2 mm)

0.61 (1.94)

G2 (≥ 2 mm)

1.46 (2.28)

G1 (≤ 2 mm)

 − 0.12 (1.89)

G2 (≥ 2 mm)

 − 2.50 (2.12)

The reduction in mandibular incisor crowding is related to the amount of initial crowding, leeway space, incisor protrusion, and increased maxillary arch width

  1. n = sample, M = male, F = female, SD = standard deviation, G1 = group 1, G2 = group 2, mx = maxilla, md = mandible, PM = premolar, M = molar, N.R. = Not reported