- Open Access
Comparison between rapid and mixed maxillary expansion through an assessment of arch changes on dental casts
© The Grassia et al. 2015
- Received: 16 April 2015
- Accepted: 26 May 2015
- Published: 27 June 2015
Aim of this retrospective observational study was to compare upper and lower dental changes in patients treated with Rapid Maxillary Expansion (RME) and Mixed Maxillary Expansion (MME), assessed by dental cast analysis.
Treatment groups consisted of 42 patients: the RME group (n = 21) consisted of 13 female and 8 male subjects with the mean age of 8.8 years ± 1.37 at T0 and 9.6 years ± 1.45 at T1; the MME group (n = 21) consisted of 12 female and 9 male patients with a mean age of 8.9 years ± 2.34 at T0 and 10.5 years ± 2.08 at T1. The upper and lower arch analysis was performed on four dental bilateral landmarks, on upper and lower casts; also upper and lower arch depths were measured. The groups were compared using independent sample t-test to estimate dental changes in upper and lower arches.
Before expansion treatment (T0), the groups were similar for all examined variables (p>0.05). In both RME and MME group, significant increments in all the variables for maxillary and mandibular arch widths were observed after treatment. No significant differences in maxillary and mandibular arch depths were observed at the end of treatment in both groups. An evaluation of the changes after RME and MME (T1) showed statistically significant differences in mandibular arch depth (p<0.001) and maxillary intercanine widths (p<0.05). Differences in maxillary arch depth and arch width measurements were not significant.
RME and MME can be considered two effective treatment options to improve transverse arch dimensions and gain space in the dental arches. A greater lower arch expansion was observed in the MME group, which might be attributed to the “lip bumper effects” observed in the MME protocol.
- Dental Arch
- Rapid Maxillary Expansion
- Mandibular Arch
- Lower Arch
- Arch Width
Skeletal expansion allows the correction of a posterior crossbite, when present [6–10]. In addition, a space gain is achieved in the arch, and the underlying permanent tooth buds are buccally repositioned [11–14].
Maxillary expansion can be performed with different methods: rapid maxillary expansion (RME) [15–17], semirapid maxillary expansion (SRME) , slow maxillary expansion (SME) [19–21] and mixed maxillary expansion (MME) [22–24]. Each treatment protocol is based on a different rationale, but all produce both skeletal and dental changes.
MME separates the two maxillary halves at the first appointment, by applying all the expansion forces to maxillary bones, thereby increasing skeletal effects and reducing unwanted dental side movements. In a previous study comparing MME-induced dento-skeletal changes on postero–anterior cephalograms in pre-pubertal patients with those in an untreated control group , MME was found to be an effective treatment option for improving dento-skeletal transverse dimensions and correcting posterior crossbite. These positive outcomes were associated with major skeletal and minor dental changes. A further research comparing the arch changes on dental casts, using the same sample and treatment procedures, confirmed the validity of MME as a useful alternative protocol for improving transverse arch dimensions and correcting posterior crossbite, as well as for gaining arch space to relieve mild-to-moderate tooth-size/arch discrepancies . A third paper compared the dento-skeletal changes on postero–anterior cephalograms in two groups of pre-pubertal patients treated with MME or RME [24, 25]. Both expansion procedures proved effective in increasing skeletal transverse dimensions by opening the mid-palatal suture in growing patients. However, MME had significantly fewer dental side effects than RME. To complete this latter research, in the light that one of the outcomes of expansion is often to increase arch widths and achieve space gain [26–31], it could be useful to investigate whether differences in arch changes were present.
Thus, the aim of this study was therefore to compare the changes in arch widths on dental casts in two groups of pre-pubertal patients treated with MME or RME.
Appropriate ethical approval was secured by the Health Research Ethics Board of the Second University of Naples (No.429), in July 22, 2014.
Consecutive records of patients treated with maxillary expansion at the Orthodontic Unit of the Second University of Naples, Italy, and in a private practice (LP) from October 2010 to March 2012 were examined. The parents of all children involved in the study gave informed consent. Inclusion criteria of this retrospective study were unilateral or bilateral posterior crossbite and/or variable degree of crowding, mixed dentition with fully erupted upper permanent molars, Cervical Vertebral Maturation Stage (CVMS) 1 or 2, treatment performed with RME or MME, dental casts, high quality latero–lateral, postero–anterior and occlusal radiographs at pre-expansion (T0) and post-expansion (T1). Exclusion criteria were cranio-facial anomalies or syndromes, periodontal diseases, dental trauma or anomalies and previous orthodontic treatment.
Characteristics of RME and MME sample groups
Total treatment duration
8 months ± 2
1.2 year ± 0.3
First: very rapid
8 months ± 2
1.3 year ± 0.2
RME group activation
In the RME group, the operator began activation at the chairside with two turns of the expansion screw (0.25 mm per turn). Parents were then instructed to continue activation at home with two turns per day.
During the expansion phase, which lasted from 1 to 3 weeks depending on the degree of maxillary constriction and/or crowding, patients were monitored once a week.
MME group activation
In the MME group, the protocol comprised two phases: an initial, very rapid opening of the device followed by a second, slower activation. The first phase, started at the chair side, included three steps with four, two and one turn (0.25 mm per turn), respectively. The three steps were carried out at the same appointment until the suture was opened.
The second expansion phase then began and parents were instructed to continue activation at home with one turn every 3 days.
During the expansion phase, which lasted from 4 to 6 months depending on the degree of maxillary constriction and/or of crowding, patients were monitored once every 2 weeks.
Clinical procedure for MME
After the first step, the patient usually experiences tenderness of the bonded teeth, which disappears in 20 to 30 min. After the second step, tenderness lasting 10–15 min then shifts to the palatal incisor area and, finally, following the third step, to the suture area. A decrease in tenderness of the bonded teeth and/or tenderness in the sutural area may indicate that the maxillary halves have been separated. However, a successful separation can only be confirmed by occlusal radiograph, before and after maxillary expansion. In the event of increased palatal suture resistance, a fourth step with two additional turns may be performed. In this case, tenderness in the temporo- and fronto-zygomatic areas may be experienced. The number of steps and associated turns therefore depends on suture intercuspidation.
After the expansion phase, the Hyrax device was removed in both groups in order to stabilize the screw with acrylic. The device was then re-cemented so that it could be used as a retainer. The retention phase lasted on average 8 months. The retention schedule of both protocols is shown in Table 1.
Digital occlusal photographs were taken of all maxillary and mandibular casts according to a standard technique and imported into Adobe Photoshop, version 5.0 (Adobe Systems, San Jose, CA). Each photograph was saved with a 5-mm grid and then imported into Scion Image (Scion, Frederick, MD; a version of the Macintosh program, NIH Image, from the National Institutes of Health). Each point in Scion was recorded to an x, y coordinate system and imported into a Microsoft Excel program to orient the coordinates and align the maxillary and mandibular casts. The dental casts were measured at T0 and T1 for each patient.
Landmarks were not recorded if the teeth were in the process of exfoliation, ectopically erupted or in the process of eruption if the height of the four outer surfaces (distal, facial, mesial and lingual) were visible.
For each tooth, the midpoint of a line connecting mesial and distal landmarks was determined, and another midpoint was constructed midway between the buccal and lingual landmarks of the tooth; the centroid is located midway between the midpoints. In the majority of teeth studied, the centroid and the midpoint between the approximal midpoints coincided or were very close to each other.
Arch width was measured between the following teeth on both arches: primary/permanent canines, first primary molars/first premolars, second primary molars/second premolars, and first permanent molars.
All measurements were carried out by the same operator. A combined error of the landmark location and tracing was determined. The method error was calculated from the double determinations of 12 randomly selected dental casts, re-measured after an interval of 1 week, using Dahlberg’s formula. The mean value of the method error was 0.5 ± 0.2 mm, within acceptable limits for the analysis of serial dental casts.
Descriptive statistics were performed on dental cast measurements at T0 and T1 for RME and MME groups.
starting forms: RME group vs. MME group at T0
treatment effects: RME group T1–T0
treatment effects: MME group T1–T0
final forms: RME group vs. MME group at T1.
All data were tested as for the normality; therefore, a parametric test was applied for the comparisons of the groups. Comparison of continuous variables between groups was made through unpaired t-tests, while changes within groups were tested through paired t-tests. The level of statistical significance set at p < .05 for all statistical tests. The statistical Package for the Social Sciences (version 22; SPSS, Chicago, III) was used for data analysis.
Characteristics of RME and MME sample groups
Mean age ± SD (year/month)
8.8 ± 1.37
9.6 ± 1.45
8.9 ± 2.39
10.5 ± 2.08
RME and MME groups were matched for number, sex, chronological age and CVMS. The RME group (n = 21) consisted of 13 girls and 8 boys with a mean age of 8.8 years ± 1.37 at T0 and 9.6 years ± 1.45 at T1. The MME group (n = 21) consisted of 12 girls and 9 boys with a mean age of 8.9 years ± 2.34 at T0 and 10.5 years ± 2.08 at T1. The CVMS ranged from 1 to 2 at T0 and from 2 to 3 at T1. The mean value of the method error was 0.5 ± 0.2 mm, within acceptable limits for the analysis of serial dental casts.
Dental cast analysis in RME and MME groups
Change after treatment
Cast measure (mm)
Maxillary arch width
Inter second premolar
Inter first premolar
Mandibular arch width
Inter second premolar
Inter first premolar
Maxillary arch depth
Mandibular arch depth
Comparison of starting forms: RME group vs. MME group at T0
Before expansion treatment (T0), the groups were similar for all width and depth measurements for maxillary and mandibular arch examined (p > 0.05).
Treatment effects: RME group T1–T0
In the RME group, significant increments in all the variables for maxillary and mandibular arch widths were observed after treatment. Maxillary intermolar, inter second premolar, inter first premolar and intercanine widths changed considerably (p < 0.001), while increases in mandibular intermolar and inter second premolar were slightly greater (p < 0.05). No significant differences in maxillary and mandibular arch depths were observed at the end of treatment.
Treatment effects: MME group T1–T0
In the MME group, significant increases in all the variables for maxillary and mandibular arch widths were observed after treatment. Maxillary intermolar, inter second premolar, inter first premolar and intercanine widths changed considerably (p < 0.001), while increases in mandibular intermolar, inter second premolar, inter first premolar (p < 0.01) and intercanine widths (p < 0.05) were slightly greater. No significant differences in maxillary and mandibular arch depths were observed at the end of treatment.
Comparison of final forms: RME group vs. MME group at T1
An evaluation of the changes after RME and MME (T1) showed statistically significant differences in mandibular arch depth (p < 0.001) and maxillary intercanine widths (p < 0.05). Differences in maxillary arch depth and arch width measurements were not significant.
The purpose of this retrospective study was to compare the changes in arch widths and depths on dental casts in two groups of pre-pubertal patients treated with MME or RME.
The method error was low, indicating the high reliability of procedures and measurements.
At baseline (T0), all the parameters were similar in the RME and MME groups (p > 0.05) and were thus comparable. All the upper measurements confirmed constriction of the dental arch associated with unilateral or bilateral posterior crossbite. In contrast, the lower values showed no abnormalities in arch widths, as reported in our previous study comparing the MME sample with an untreated control group .
After treatment, significant increases in upper and lower arch widths were observed in both the RME and MME group.
Changes in the upper arch intermolar, inter second premolar, inter first premolar and intercanine widths were significant (p < 0.001) in both groups.
Lower arch changes were significant for intermolar and inter second premolar in both the MME (p < 0.01) and RME (p < 0.05) group, whereas increases in inter first premolar (p < 0.01) and intercanine widths (p < 0.05) were significant only in the MME group. Conversely, no significant differences in upper and lower arch depth between the groups were noted.
Therefore, both procedures were found to be useful for increasing upper arch widths and gaining space to resolve unilateral or bilateral posterior crossbite and/or mild-to-moderate upper crowding.
However, as previously reported, the expansion obtained with MME presents minor dental side effects [22–24]. We may thus speculate that, although comparable at T1 in both groups, the increase in transverse diameters in the upper arch following MME is due to skeletal basal expansion rather than dental tipping. Upper arch changes obtained with MME are therefore subject to less relapse and consequently more stable.
A larger increase in lower widths was found in the MME group. This could be explained by a greater “lip bumper effect” observed after MME [23, 32]. When the upper widths increased slowly during the second step of activation, the cheeks were distanced from the buccal surfaces of mandibular teeth, causing the lower teeth to upright. Uprighting was greater in the molar than in the canine area as a consequence of greater posterior upper arch changes.
At T1, the two groups overlapped for all measurement increases, except for upper intercanine width (p < 0.05) and mandibular arch depth (p < 0.001). The difference in upper intercanine width is likely a result of the greater anterior opening of the mid-palatal suture, a consequence of increased skeletal expansion obtained by MME, as shown in our previous studies [22–24].
Interestingly, a statistically significant difference in mandibular arch depth between the two groups was observed. The loss in mandibular depth in the MME group might be related to the greater increase in transversal lower arch dimensions compared to the RME group. This study had some limitations. The first is due to the observational design although randomized controlled trials (RCTs) in orthodontic research are still very rare. Second, the small size of the sample can be explained with the very restrictive inclusion criteria. Third, the error method was low, but it does not mean high reliability, so the validity may be not high.
Our future goals are to compare the results obtained with MME and RME through the analysis of the cone beam for skeletal pattern and 3D model analysis for dental arches changes.
RME and MME can be considered two effective treatment options to improve transverse arch dimensions and gain space in the dental arches. Few statistically significant differences in measurements of dental changes were found. RME and MME were both effective in increasing dental transverse dimensions by opening the mid-palatal suture in growing patients. A greater lower arch expansion was observed in the MME group, which might be attributed to the “lip bumper effects” observed in the MME protocol.
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